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Major Depressive Disorder

There is help

Depression is a common and serious medical illness that negatively affects how you feel, the way you think and how you act. Depression often causes feelings of sadness and/or a loss of interest in activities once enjoyed or false feelings of happiness through codependence

The most common modes of treatment are usually medication, talk therapy, or a combination of the two with licensed professionals. Increasingly, research suggests these treatments may normalize brain changes associated with depression.

Mental Health

Clinical Research ENROLLING NOW

The RELIANCE Clinical Research Program is investigating a medication for people living with depression. Even with treatment, depression symptoms may continue. That is why researchers are exploring how an investigational medication may help to manage depression when taken alone or when added to existing antidepressants. If you are not taking an antidepressant or currently take antidepressants but find that they are not fully managing your symptoms, one of these studies may be an option for you.

You may be eligible to participate if:

  • you have been diagnosed with depression and are currently experiencing symptoms

  • you are between the ages of 18-65 years old

Sunrise over the Wheat Field

About the Study

Clinical Research Program is currently testing an investigational medication for people living with depression. If you have been diagnosed with depression, are currently experiencing symptoms, sometimes referred to as a depressive episode, and are between the ages of 18-65 years, you may be eligible to participate.

This program includes studies for people who are not currently taking an antidepressant or who are currently taking antidepressants but find that they are not fully managing your symptoms. If you are taking an antidepressant and are eligible for one of these studies, you may be able to continue with your current antidepressant in addition to using the investigational medication.

People who enroll in a study will be randomly assigned (like the flip of a coin) to a study treatment group to take either the investigational medication or a placebo. There is an equal chance (50/50) of being assigned to either group. Neither you nor the study doctor will know whether you are assigned to the treatment or placebo group. After completing one of these studies, as a participant you will have the opportunity to join a longer open label study. In the open label study, all participants will receive the investigational medication for up to 1 year. The purpose of this open label study is to continue evaluating the investigational medication over a longer treatment period.

MDD Form
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